A direct measurement of the radiation sensitivity of normal mouse bone marrow cells

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RadRes_1961_14_213.pdf (657.54 KB)

Date

1961-02

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Radiation Research Society

Abstract

SUMMARY: 1. A direct technique for the measurement of the number of cells in a bone marrow suspension capable of continued proliferation is described. 2. The technique was used to measure the radiation sensitivity of normal mouse bone marrow cells and yielded a Do of 115 ± 8 rads.

Description

Counts of macroscopic splenic colonies were used to obtain an estimate of the radiation sensitivity of normal mouse bone marrow progenitor cells. Reproduced from Radiation Research 1961(Feb); 14(2): 213-222 by copyright permission of the Radiation Research Society (www.radres.org).

Keywords

bone marrow cells, CFU, colony-forming units, hematopoietic progenitor cells, hematopoietic stem cells, hematopoietic stem cell transplantation, inbred mouse strains, mouse marrow, radiation sensitivity, spleen colonies

Citation

Radiation Research 1961(Feb); 14(2): 213-222

URI

http://hdl.handle.net/1807/2781

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Stem Cells
Till, James E.
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