Hemoglobin Threshold for Blood Transfusion in Young Children Hospitalized with Iron Deficiency Anemia

Abstract

Current recommendations advise against blood transfusion in hemodynamically stable children with iron deficiency anemia (IDA). In an observational study of 125 children ages 6 through 36 months, hospitalized with IDA, we found that hemoglobin level predicted red blood cell transfusion (area under the curve 0.8862). A hemoglobin of 39 g/L had sensitivity 92% and specificity 72% for transfusion.

Description

This is the pre-print/submitted manuscript version of an Article-in-Press published by Elsevier.

Keywords

hemoglobin, hemodynamic instability, inpatient care, transfusion complications, receiver operating curves, area under the curve, sensitivity, specificity

Citation

Rose Sun DL, Puran A, Al Nuaimi M, AlRiyami L, Kinlin LM, Kirby-Allen M, Mahant S, Gill PJ, Borkhoff CM, Parkin PC, Hemoglobin Threshold for Blood Transfusion in Young Children Hospitalized with Iron Deficiency Anemia, The Journal of Pediatrics (2024), doi: https:// doi.org/10.1016/j.jpeds.2023.113878.

DOI

10.1016/j.jpeds.2023.113878

ISSN

00223476

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