Towards a Quantitative Colorimetric Gold Nanoparticle-Based Assay for Measuring ppm and Sub-ppm Aqueous Nitrite Levels

dc.contributor.advisor	Ramchandran, Arun
dc.contributor.author	Lin, Yuan-Kai
dc.contributor.department	Chemical Engineering Applied Chemistry
dc.date	2019-11
dc.date.accepted	2019-11
dc.date.accessioned	2024-11-20T05:00:25Z
dc.date.available	2024-11-20T05:00:25Z
dc.date.convocation	2019-11
dc.date.issued	2019-11
dc.description.abstract	Prior publications and work from our group have demonstrated a colorimetric assay coupling the Griess reaction with gold nanoparticle aggregation to detect the concentration of nitrites. However, a major disadvantage of this assay is it is slow and needs to be conducted at 95oC. This project takes a closer look at the mechanism of aggregation and lower the reaction temperature. The modifications allow the colorimetric measurement of nitrite concentrations exceeding 230 M (10 ppm) at room temperature, greater than 3 M (130 ppb) at 50oC, and potentially as low as about 0.05 M (2 ppb) at 95oC. This work sets the foundation for the development of an accurate, precise, inexpensive and portable nitrite measurement kit.
dc.description.degree	M.A.S.
dc.description.embargo	2024-11-20 00:00:00
dc.identifier.uri	http://hdl.handle.net/1807/141415
dc.subject	Gold
dc.subject	Nanoparticle
dc.subject	Nitrate
dc.subject	Nitrite
dc.subject	Sensor
dc.subject.classification	0652
dc.title	Towards a Quantitative Colorimetric Gold Nanoparticle-Based Assay for Measuring ppm and Sub-ppm Aqueous Nitrite Levels
dc.type	Thesis

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