Comparative Evaluation of Seven Commercial Tests for Detection of Heterophile Antibody in Infectious Mononucleosis

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1992-01-01

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Abstract

Detection of heterophile antibodies in infectious mononucleosis is the most rapid and cost-effective method for confirming the clinical diagnosis of the disease. This study compared seven commercial test kits (the Oxoid Infectious Mononucleosis Kit [Oxoid Ltd], Immunoscan Im-Latex [Baxter Travenol], Mono-Latex [Wampole Laboratories], Monospot and Im Screen Test [Ortho Diagnostics], Immunoscan Im-RBC Test [Baxter Travenol], and Infectious Mononucleosis Test [NCS Diagnostics]) to the Davidsohn differential test. All of the kits were shown to be acceptable for use, with specificities and sensitivities greater than 96.5% and 95.5%, respectively.

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Martin Skulnick, Donald E Low, Andrew E Simor, Mohan Patel, Pauline George, and Robert Chua, “Comparative Evaluation of Seven Commercial Tests for Detection of Heterophile Antibody in Infectious Mononucleosis,” Canadian Journal of Infectious Diseases, vol. 3, no. 1, pp. 23-26, 1992. doi:10.1155/1992/510261

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http://hdl.handle.net/1807/82265

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https://doi.org/10.1155/1992/510261

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https://creativecommons.org/licenses/by/4.0/

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